top of page
Asset 10_3x.png
DNA-level editing of microbial communities for understanding and control.
Overview
  • Microbial communities are major contributors to the uptake and release of greenhouse gasses and are critical regulators of human health; however, efforts to precisely engineer their constituents' DNA are nascent. Our laboratory at the University of California, Berkeley brings DNA-editing tools to microbiomes.

  • In the short term, this approach should provide understanding of the interactions and unstudied organisms within communities.

  • Over the longer term, community editing offers a precise means for controlling microbiomes that are instrumental to our health, agriculture, climate, and industry.

bafkreibrp4uxavziafdkjfzmd7md6566njg54gbzmahqyt4itslc5eatci.jpg

Publication Alert

January 1, 2026

Starting the New Year off with a new publication on CAST regulators from Amanda and Leo in Science Advances!

bafkreigdmm3wngdukapw4iruga676upv6jspn37d7dhnqyhwqwnk75os5a.jpg

Publication Alert

December 11, 2025

Our lab's first lead paper—on developing a language model to generate functional plasmid origins—is out in Nucleic Acids Research!

Higher Quality.png

The Lab

November 1, 2025

We welcome new undergrads Varsha, Ashley, and Hengyi to the lab!

IMG_7575.jpg

Social

May 30, 2025

The Rubin and Cress Labs celebrate the start of summer with a rooftop BBQ!

Funders
60359a3141e7431071cc41d4_the-audacious-project-logo.png
Helmsley_EPS_for_PC-removebg-preview.png
bottom of page